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Merck

IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

Sinonimi:
CD130, CDW130, GP130, IL-6RB
Specie:
ID UniProtKB:
ID gene:
  • Human(3572) Summary: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010]
  • Mouse(16195) interleukin 6 signal transducer
  • Rat(25205) interleukin 6 signal transducer
  • Domestic Rabbit(100349330) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • sheep(101113174) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • cow(522155) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Horse(100051700) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • domestic cat(101089832) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • dog(403545) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • chicken(395684) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • naked mole-rat(101703833) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Zebrafish(100006778) interleukin 6 signal transducer

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human sgp130 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-IL6ST antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-CD130 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-IL6ST antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, guinea pig, horse, human, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti- IL6ST antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-CD130/IL-6RB Antibody, clone 2I13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
canine, horse, human, monkey, porcine, rat
Applicazione
affinity binding assay
immunocytochemistry

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human IL6ST,
Specie
human
MISSION® esiRNA, targeting mouse Il6st,
Specie
mouse