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Merck

IL7R

interleukin 7 receptor

Sinonimi:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Specie:
ID UniProtKB:
ID gene:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Mouse Il7r / Interleukin-7 Receptor Subunit Alpha ELISA Kit, ,
Specie
mouse
Human IL-7 R alpha ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-IL7R antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
mouse, rat
Applicazione
ELISA
western blot
Anti-CD127 (IL-7Ra) Antibody (mouse), PE-Cy7, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), PE-Cy7, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human IL7R,
Specie
human