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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Sinonimi:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Specie:
ID UniProtKB:
ID gene:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Ribavirin, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Ribavirin, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Ribavirin, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Ribavirin impurity standard, British Pharmacopoeia (BP) Reference Standard,
Specie
human
Ribavirin, British Pharmacopoeia (BP) Reference Standard,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human IMPDH1,
Specie
human
MISSION® esiRNA, targeting mouse Impdh1,
Specie
mouse