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Merck

IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

Sinonimi:
IMPD2, IMPDH-II
Specie:
ID UniProtKB:
ID gene:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunoprecipitation (IP)

western blot
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Reattività con
human
Applicazione
Anti IMPDH2 Antibody, clone 23GB6670, Rabbit Monoclonal, clone 23GB6670, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
β-Nicotinamide adenine dinucleotide, reduced dipotassium salt, ,
Specie
human
6-Thioguanine, ≥98%,
Specie
human
Mycophenolic acid, ≥98%,
Specie
human
Ribavirin, antiviral,
Specie
human
Mycophenolate mofetil, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human IMPDH2,
Specie
human
MISSION® esiRNA, targeting mouse Impdh2,
Specie
mouse