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Merck

IYD

iodotyrosine deiodinase

Sinonimi:
C6orf71, DEHAL1, TDH4, dJ422F24.1
Specie:
ID UniProtKB:
ID gene:
  • Human(389434) Summary: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  • Mouse(70337) iodotyrosine deiodinase
  • Rat(308129) iodotyrosine deiodinase
  • naked mole-rat(101721889) iodotyrosine deiodinase
  • domestic guinea pig(100728406) iodotyrosine deiodinase
  • sheep(101123564) iodotyrosine deiodinase
  • Zebrafish(568107) iodotyrosine deiodinase
  • domestic cat(101100136) iodotyrosine deiodinase
  • dog(476244) iodotyrosine deiodinase
  • chicken(421631) iodotyrosine deiodinase
  • cow(534110) iodotyrosine deiodinase

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-IYD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human IYD,
Specie
human
MISSION® esiRNA, targeting mouse Iyd,
Specie
mouse