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Merck

LEF1

lymphoid enhancer-binding factor 1

Sinonimi:
LEF-1, TCF10, TCF1ALPHA, TCF7L3
Specie:
ID UniProtKB:
ID gene:
  • Human(51176) Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(16842) lymphoid enhancer binding factor 1
  • Rat(161452) lymphoid enhancer binding factor 1
  • domestic guinea pig(100716066) lymphoid enhancer-binding factor 1
  • naked mole-rat(101711023) lymphoid enhancer-binding factor 1
  • dog(478507) lymphoid enhancer-binding factor 1
  • Zebrafish(30701) lymphocyte enhancer binding factor 1
  • domestic cat(101088077) lymphoid enhancer-binding factor 1
  • cow(535399) lymphoid enhancer-binding factor 1
  • chicken(395865) lymphoid enhancer-binding factor 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-LEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
ChIP
immunofluorescence

immunohistochemistry

western blot
ChIPAb+ LEF1 - ChIP Validated Antibody and Primer Set, from mouse,
Reattività con
human, mouse
Applicazione
ChIP
western blot
Anti-LEF1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, goat, human
Applicazione
western blot
Anti-LEF1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-LEF1 antibody produced in mouse, clone 5A3, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human LEF1,
Specie
human