MADD
MAP-kinase activating death domain
Sinonimi:
DENN, IG20, RAB3GEP
Specie:
Human MADD (8567), Mouse Madd (228355), Rat Madd (94193), sheep MADD (101117276), domestic guinea pig Madd (100725450), naked mole-rat Madd (101710698), cow MADD (534306), Horse MADD (100051327), domestic cat MADD (101093297), dog MADD (475982) ...Più
ID UniProtKB:
ID gene:
- Human(8567) Summary: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(228355) MAP-kinase activating death domain
- Rat(94193) MAP-kinase activating death domain
- sheep(101117276) MAP-kinase activating death domain
- domestic guinea pig(100725450) MAP-kinase activating death domain
- naked mole-rat(101710698) MAP-kinase activating death domain
- cow(534306) MAP-kinase activating death domain
- Horse(100051327) MAP-kinase activating death domain
- domestic cat(101093297) MAP-kinase activating death domain
- dog(475982) MAP-kinase activating death domain
- chicken(423184) MAP-kinase activating death domain
- Zebrafish(100150917) MAP-kinase activating death domain
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MADD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MADD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
KD-Validated Anti MAP Kinase Activating Death Domain Antibody, clone 24GB110, Rabbit Monoclonal, clone 24GB110, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot