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Merck

MARCH2

membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

Sinonimi:
MARCH-II, RNF172
Specie:
Human MARCH2 (51257), Mouse March2 (224703), Rat March2 (362849), Zebrafish march2 (555611), domestic guinea pig March2 (100733733), domestic cat MARCH2 (101090087), cow MARCH2 (508949), dog MARCH2 (611624), naked mole-rat March2 (101720054), sheep MARCH2 (101103806)
ID UniProtKB:
Q9P0N8, A6NP10, Q5H785, Q8N5A3, Q96B78
ID gene:
  • Human(51257) Summary: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(224703) membrane-associated ring finger (C3HC4) 2
  • Rat(362849) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • Zebrafish(555611) membrane-associated ring finger (C3HC4) 2
  • domestic guinea pig(100733733) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • domestic cat(101090087) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • cow(508949) membrane-associated ring finger (C3HC4) 2
  • dog(611624) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • naked mole-rat(101720054) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • sheep(101103806) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • chicken(420062) membrane-associated ring finger (C3HC4) 2

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB1403235
Monoclonal Anti-MARCH2 antibody produced in mouse, clone 7F3, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
EHU036831
MISSION® esiRNA, targeting human MARCH2,
Specie
human