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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

Sinonimi:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Specie:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), cow MTOR (100139219), Horse MTOR (100051341), Goat MTOR (100860902), dog MTOR (478232), sheep MTOR (100271659), domestic guinea pig Mtor (100724938), chicken MTOR (419455) ...Più
ID UniProtKB:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
ID gene:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
ABS79
Anti-phospho-mTOR (Ser2159) Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat, sheep, zebrafish
Applicazione
dot blot
inhibition assay
western blot
SAB4504476
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
SAB4501038
Anti-MTOR antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
SAB4301415
Anti-phospho-mTOR (pThr2446) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
SAB5700327
Anti-Phospho-mTOR-S2448 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Specie
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU101641
MISSION® esiRNA, targeting human MTOR,
Specie
human