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Merck

OTX2

orthodenticle homeobox 2

Sinonimi:
CPHD6, MCOPS5
Specie:
ID UniProtKB:
ID gene:
  • Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
  • Mouse(18424) orthodenticle homolog 2 (Drosophila)
  • Rat(305858) orthodenticle homeobox 2
  • domestic guinea pig(100729098) orthodenticle homeobox 2
  • domestic cat(101094107) orthodenticle homeobox 2
  • naked mole-rat(101696878) orthodenticle homeobox 2
  • sheep(101114527) orthodenticle homeobox 2
  • chicken(395191) orthodenticle homeobox 2
  • cow(538953) orthodenticle homeobox 2
  • Domestic Rabbit(100009374) orthodenticle homeobox 2
  • Zebrafish(30501) orthodenticle homolog 2
  • dog(490708) orthodenticle homeobox 2

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-OTX2, from rabbit, purified by affinity chromatography,
Reattività con
bovine, human, rat, rhesus macaque
Applicazione
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
ChIP
immunohistochemistry
Anti-OTX2 Antibody, clone 8D8.2, clone 8D8.2, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Reattività con
human
Applicazione
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human OTX2,
Specie
human
MISSION® esiRNA, targeting mouse Otx2,
Specie
mouse