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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Sinonimi:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Specie:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...Più
ID UniProtKB:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
ID gene:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Specie
human
V6383
Vinpocetine, ≥98%, solid,
Specie
human
1220506
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Y0000802
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Specie
human
D2850000
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU074801
MISSION® esiRNA, targeting human PDE1A,
Specie
human
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
Specie
mouse