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Merck

PDHB

pyruvate dehydrogenase (lipoamide) beta

Sinonimi:
PDHBD, PDHE1-B, PHE1B
Specie:
ID UniProtKB:
ID gene:
  • Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
  • Rat(289950) pyruvate dehydrogenase (lipoamide) beta
  • sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
  • cow(613610) pyruvate dehydrogenase (lipoamide) beta
  • Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
  • domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
  • dog(476574) pyruvate dehydrogenase (lipoamide) beta
  • chicken(416066) pyruvate dehydrogenase (lipoamide) beta
  • domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
  • Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
  • naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-PDHB antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot

Kits

Numero di prodotto
Descrizione
Specie
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Specie
rat, mouse, human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human PDHB,
Specie
human
MISSION® esiRNA, targeting mouse Pdhb,
Specie
mouse