PRCP
prolylcarboxypeptidase (angiotensinase C)
Sinonimi:
HUMPCP, PCP
Specie:
Human PRCP (5547), Mouse Prcp (72461), Rat Prcp (293118), sheep PRCP (101107644), Horse PRCP (100061830), domestic cat PRCP (101100665), cow PRCP (534927), naked mole-rat Prcp (101719590), chicken PRCP (428096), dog PRCP (476788) ...Più
ID UniProtKB:
ID gene:
- Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
- Rat(293118) prolylcarboxypeptidase (angiotensinase C)
- sheep(101107644) prolylcarboxypeptidase (angiotensinase C)
- Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
- domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
- cow(534927) prolylcarboxypeptidase (angiotensinase C)
- naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
- chicken(428096) prolylcarboxypeptidase (angiotensinase C)
- dog(476788) prolylcarboxypeptidase (angiotensinase C)
- Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
- domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)
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ELISA
Numero di prodotto
Descrizione
Specie
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Proteins
Numero di prodotto
Descrizione
Specie
PrCP active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥15% (SDS-PAGE),
Specie
human