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Merck

RARB

retinoic acid receptor, beta

Sinonimi:
HAP, NR1B2, RRB2
Specie:
ID UniProtKB:
ID gene:
  • Human(5915) Summary: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(218772) retinoic acid receptor, beta
  • Rat(24706) retinoic acid receptor, beta
  • Domestic Rabbit(100358445) retinoic acid receptor, beta
  • sheep(101122663) retinoic acid receptor, beta
  • cow(616895) retinoic acid receptor, beta
  • Horse(100051546) retinoic acid receptor, beta
  • domestic cat(101085742) retinoic acid receptor, beta
  • dog(477045) retinoic acid receptor, beta
  • domestic guinea pig(100379264) retinoic acid receptor, beta
  • chicken(396266) retinoic acid receptor, beta
  • naked mole-rat(101724485) retinoic acid receptor, beta

Custom & Knockdown Gene Products

Small Molecule - Activator

Numero di prodotto
Descrizione
Specie
9-cis-Retinoic acid, ≥98% (HPLC),
Specie
human
Acido retinoico, ≥98% (HPLC), powder,
Specie
mouse, human

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
AM580, ≥98% (HPLC),
Specie
human
Acido retinoico, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Isotretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Acido retinoico, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Isotretinoin, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
AM580, ≥98% (HPLC),
Specie
human
CD437, ≥98% (HPLC), solid,
Specie
human
TTNPB, ,
Specie
human
Acido retinoico, ≥98% (HPLC), powder,
Specie
mouse, human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Retinoic Acid Receptor β, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunohistochemistry

western blot

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
9-cis-Retinoic acid, ≥98% (HPLC),
Specie
human
TTNPB, ,
Specie
human
Acido retinoico, ≥98% (HPLC), powder,
Specie
mouse, human

Small Molecule - Mixed Agonist/Antagonist

Numero di prodotto
Descrizione
Specie
Acido retinoico, ≥98% (HPLC), powder,
Specie
mouse, human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human RARB,
Specie
human
MISSION® esiRNA, targeting mouse Rarb,
Specie
mouse