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Merck

SETMAR

SET domain and mariner transposase fusion gene

Sinonimi:
HsMar1, METNASE, Mar1
Specie:
ID UniProtKB:
ID gene:
  • Human(6419) Summary: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(74729) SET domain without mariner transposase fusion
  • Rat(500281) SET domain without mariner transposase fusion
  • naked mole-rat(101704237) SET domain and mariner transposase fusion gene
  • domestic cat(101088560) SET domain without mariner transposase fusion
  • cow(511299) SET domain without mariner transposase fusion
  • Zebrafish(564575) SET domain without mariner transposase fusion
  • dog(476549) SET domain without mariner transposase fusion
  • sheep(101110273) SET domain gene

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-SETMAR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
western blot

Proteins

Numero di prodotto
Descrizione
Specie
SETMAR, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
Metnase (SETMAR) human, recombinant, expressed in FreeStyle 293-F cells, ≥30% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Setmar,
Specie
mouse
MISSION® esiRNA, targeting human SETMAR,
Specie
human