STAT2
signal transducer and activator of transcription 2, 113kDa
Sinonimi:
ISGF-3, P113, STAT113
Specie:
Human STAT2 (6773), Mouse Stat2 (20847), Rat Stat2 (288774), dog STAT2 (481111), sheep STAT2 (101108211), cow STAT2 (511023), naked mole-rat Stat2 (101707295), domestic cat STAT2 (101099224), domestic guinea pig Stat2 (100719719), Zebrafish stat2 (565200)
ID UniProtKB:
ID gene:
- Human(6773) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
- Mouse(20847) signal transducer and activator of transcription 2
- Rat(288774) signal transducer and activator of transcription 2
- dog(481111) signal transducer and activator of transcription 2, 113kDa
- sheep(101108211) signal transducer and activator of transcription 2, 113kDa
- cow(511023) signal transducer and activator of transcription 2, 113kDa
- naked mole-rat(101707295) signal transducer and activator of transcription 2, 113kDa
- domestic cat(101099224) signal transducer and activator of transcription 2, 113kDa
- domestic guinea pig(100719719) signal transducer and activator of transcription 2, 113kDa
- Zebrafish(565200) signal transducer and activator of transcription 2
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti STAT2 Antibody, clone 24GB2095, Rabbit Monoclonal, clone 24GB2095, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-STAT2 (Tyr689) Antibody, Upstate®, from rabbit,
Reattività con
human, mouse
Applicazione
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Anti-phospho-STAT2 (pTyr690) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-STAT2 (Tyr689) Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-STAT2 Antibody, clone 1F7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot