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Merck

TGFB1

transforming growth factor, beta 1

Sinonimi:
CED, DPD1, LAP, TGFB, TGFbeta
Specie:
ID UniProtKB:
ID gene:
  • Human(7040) Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
  • Mouse(21803) transforming growth factor, beta 1
  • Rat(59086) transforming growth factor, beta 1
  • sheep(443417) transforming growth factor, beta 1
  • domestic cat(768263) transforming growth factor, beta 1
  • naked mole-rat(101704230) transforming growth factor, beta 1
  • dog(403998) transforming growth factor, beta 1
  • Domestic Rabbit(100008645) transforming growth factor, beta 1
  • chicken(100873157) transforming growth factor beta 1
  • cow(282089) transforming growth factor, beta 1
  • Horse(100033900) transforming growth factor, beta 1
  • domestic guinea pig(100135628) transforming growth factor, beta 1

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human TGF-β 1 ELISA Kit, for serum, plasma, and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-TGF β1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-TGFB1, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-TGF-β1 Antibody, clone 4E3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, goat, horse, human, monkey, nonhuman primates, porcine, rat, sheep
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-TGFB1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-TGFB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

Proteins

Numero di prodotto
Descrizione
Specie
Fattore di crescita trasformante-β1, TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture,
Specie
human
Fattore di crescita trasformante-β1, TGF-β1, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Specie
human
Transforming Growth Factor-β1, human (hTGF-β1), recombinant (CHO cells),
Specie
human
Transforming Growth Factor-β1 Latency Associated Peptide human, ≥97% (SDS-PAGE), recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human TGFB1,
Specie
human
MISSION® esiRNA, targeting mouse Tgfb1,
Specie
mouse