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Merck

TIMP2

TIMP metallopeptidase inhibitor 2

Sinonimi:
CSC-21K, DDC8
Specie:
ID UniProtKB:
ID gene:
  • Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(21858) tissue inhibitor of metalloproteinase 2
  • Rat(29543) TIMP metallopeptidase inhibitor 2
  • Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
  • domestic cat(101083125) TIMP metallopeptidase inhibitor 2
  • Horse(100034134) TIMP metallopeptidase inhibitor 2
  • dog(403633) TIMP metallopeptidase inhibitor 2
  • cow(282093) TIMP metallopeptidase inhibitor 2
  • chicken(374178) TIMP metallopeptidase inhibitor 2
  • domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
  • naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
  • sheep(100217406) TIMP metallopeptidase inhibitor 2

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human TIMP-2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Porcine TIMP2 / Tissue Inhibitor of Metalloproteinase-2 ELISA Kit, ,
Specie
Rat TIMP-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
rat
Canine TIMP2 / Metalloproteinase Inhibitor 2 ELISA Kit, ,
Specie
dog
Mouse TIMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-TIMP-2 Antibody, clone 2TMP05, clone 2TMP05, Chemicon®, from mouse,
Reattività con
bovine, guinea pig, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti-TIMP2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

western blot
Anti-TIMP2 antibody, Mouse monoclonal, clone TM8, purified from hybridoma cell culture,
Reattività con
human
Applicazione
immunofluorescence
western blot
Anti-TIMP-2 Antibody, clone 67-4H11, clone 67-4H11, Chemicon®, from mouse,
Reattività con
bovine, goat, guinea pig, human, mouse, rabbit, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-TIMP2 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot

Proteins

Numero di prodotto
Descrizione
Specie
TIMP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human TIMP2,
Specie
human
MISSION® esiRNA, targeting mouse Timp2,
Specie
mouse