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Merck

TLR7

toll-like receptor 7

Sinonimi:
TLR7-like
Specie:
ID UniProtKB:
ID gene:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • dog(491743) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
Imiquimod, ≥98% (HPLC), solid,
Specie
human
Imiquimod, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Specie
human
Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Hydroxychloroquine sulfate, analytical standard,
Specie
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry

western blot
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
Reattività con
human
Applicazione
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human TLR7,
Specie
human
MISSION® esiRNA, targeting mouse Tlr7,
Specie
mouse