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Merck

TNF

tumor necrosis factor

Sinonimi:
DIF, TNF-alpha, TNFA, TNFSF2
Specie:
ID UniProtKB:
ID gene:
  • Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
  • Mouse(21926) tumor necrosis factor
  • Rat(24835) tumor necrosis factor
  • dog(403922) tumor necrosis factor
  • domestic cat(493755) tumor necrosis factor
  • Horse(100033834) tumor necrosis factor
  • Goat(100861232) tumor necrosis factor alpha
  • cow(280943) tumor necrosis factor
  • sheep(443540) tumor necrosis factor
  • Domestic Rabbit(100009088) tumor necrosis factor
  • domestic guinea pig(100135630) tumor necrosis factor
  • naked mole-rat(101718432) tumor necrosis factor

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Mouse Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
Rat Tumor Necrosis Factor α ELISA Kit, for cell and tissue lysates,
Specie
rat
Rat Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
rat
Porcine Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
Canine TNF / Tumor Necrosis Factor ELISA Kit, for serum, plasma and cell culture supernatants,
Specie
dog

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Abietic acid, technical, ~75% (GC),
Specie
human
Podocarpic acid, 98%,
Specie
human
Forskolina, from Coleus forskohlii, ≥98% (HPLC), powder,
Specie
human
Myricetin, ≥96.0% (HPLC),
Specie
rat, mouse, human
Myricetin, ≥96.0%, crystalline,
Specie
rat, mouse, human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-TNF-α antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-TNF-α antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-TNFA antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry
Anti-TNFα Antibody, clone 3B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
ELISA
affinity binding assay

immunocytochemistry

western blot
Anti-TNF-α Rabbit pAb, liquid, Calbiochem®,
Reattività con
human, mouse
Applicazione

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
SPD304, ≥98% (HPLC), solid,
Specie
mouse, rat, human
Myricetin, ≥96.0% (HPLC),
Specie
rat, mouse, human
Myricetin, ≥96.0%, crystalline,
Specie
rat, mouse, human
(−)-Thalidomide, >98%, solid,
Specie
human, mouse, rat
(+)-Thalidomide, ≥98% (HPLC), powder,
Specie
human, mouse, rat

Proteins

Numero di prodotto
Descrizione
Specie
Tumor Necrosis Factor-α human, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Specie
human
TNF-α human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
Specie
human
Tumor Necrosis Factor-α human, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
Specie
human
Tumor Necrosis Factor-α from mouse, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
Specie
mouse
Fattore di necrosi tumorale-α proteina ricombinante umana., Tumor Necrosis Factor-alpha (TNF-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells & certain other target cells.,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Tnf,
Specie
mouse
MISSION® esiRNA, targeting human TNF,
Specie
human