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Merck

UCP1

uncoupling protein 1 (mitochondrial, proton carrier)

Sinonimi:
SLC25A7, UCP
Specie:
ID UniProtKB:
ID gene:
  • Human(7350) Summary: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008]
  • Mouse(22227) uncoupling protein 1 (mitochondrial, proton carrier)
  • Rat(24860) uncoupling protein 1 (mitochondrial, proton carrier)
  • dog(403574) uncoupling protein 1 (mitochondrial, proton carrier)
  • domestic guinea pig(100722020) uncoupling protein 1 (mitochondrial, proton carrier)
  • Zebrafish(83908) uncoupling protein 1
  • Domestic Rabbit(100328618) uncoupling protein 1 (mitochondrial, proton carrier)
  • domestic cat(101089511) uncoupling protein 1 (mitochondrial, proton carrier)
  • naked mole-rat(101723752) uncoupling protein 1 (mitochondrial, proton carrier)
  • cow(281561) uncoupling protein 1 (mitochondrial, proton carrier)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticopo anti-proteina di disaccoppiamento 1, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-UCP1, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-UCP1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Monoclonal Anti-UCP1 antibody produced in mouse, clone 4B7, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
western blot
Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb, liquid, Calbiochem®,
Reattività con
human, mouse, rat
Applicazione

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human UCP1,
Specie
human