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Merck

UMPS

uridine monophosphate synthetase

Sinonimi:
OPRT
Specie:
ID UniProtKB:
ID gene:
  • Human(7372) Summary: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
  • Mouse(22247) uridine monophosphate synthetase
  • Rat(288051) uridine monophosphate synthetase
  • domestic cat(101095364) uridine monophosphate synthetase
  • naked mole-rat(101699019) uridine monophosphate synthetase
  • dog(478593) uridine monophosphate synthetase
  • cow(281568) uridine monophosphate synthetase
  • sheep(780512) uridine monophosphate synthetase
  • sheep(101116528) uridine monophosphate synthetase
  • Zebrafish(393143) uridine monophosphate synthetase
  • chicken(424256) uridine monophosphate synthetase
  • domestic guinea pig(100726089) uridine monophosphate synthetase
  • Horse(100070386) uridine monophosphate synthetase
  • Domestic Rabbit(100353794) uridine monophosphate synthetase

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-UMPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-UMPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-UMPS antibody produced in mouse, clone 2F5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human UMPS,
Specie
human
MISSION® esiRNA, targeting mouse Umps,
Specie
mouse