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Merck

WISP3

WNT1 inducible signaling pathway protein 3

Sinonimi:
CCN6, LIBC, PPAC, PPD
Specie:
ID UniProtKB:
ID gene:
  • Human(8838) Summary: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(327743) WNT1 inducible signaling pathway protein 3
  • Rat(499461) WNT1 inducible signaling pathway protein 3
  • domestic guinea pig(100727845) WNT1 inducible signaling pathway protein 3
  • Horse(100072430) WNT1 inducible signaling pathway protein 3
  • cow(784564) WNT1 inducible signaling pathway protein 3
  • chicken(770827) WNT1 inducible signaling pathway protein 3
  • cow(100849041) WNT1 inducible signaling pathway protein 3
  • Zebrafish(794092) WNT1 inducible signaling pathway protein 3
  • domestic cat(101086230) WNT1 inducible signaling pathway protein 3
  • naked mole-rat(101697161) WNT1 inducible signaling pathway protein 3
  • dog(100686448) WNT1 inducible signaling pathway protein 3
  • sheep(101109099) WNT1 inducible signaling pathway protein 3

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-WISP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence

Proteins

Numero di prodotto
Descrizione
Specie
WISP-3 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human WISP3,
Specie
human
MISSION® esiRNA, targeting mouse Wisp3,
Specie
mouse