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For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
O1008
Oleic acid
≥99% (GC)
Synonym(s):
9Z-Octadecenoic acid, cis-Oleic acid, cis-9-Octadecenoic acid, Elainic acid
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CLP 39,000
CLP 119,000
CLP 381,000
About This Item
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Product Name
Oleic acid, ≥99% (GC)
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
biological source
plant (Sunflower)
vapor pressure
1 mmHg ( 176 °C)
assay
≥99% (GC)
form
viscous liquid
color
colorless to very faintly yellow
refractive index
n20/D 1.459 (lit.)
bp
194-195 °C/1.2 mmHg (lit.)
mp
13-14 °C (lit.)
solubility
H2O: insoluble (practically)
alcohol: soluble
benzene: soluble
chloroform: soluble
oil: soluble (fixed and volatile)
density
0.89 g/mL at 25 °C (lit.)
application(s)
life science and biopharma
lipidomics
functional group
oleic acid
lipid type
unsaturated FAs
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584), SOAT1(6646), SOAT2(8435)
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Related Categories
1 of 4
This Item | W281506 | 364525 | 27728 |
|---|---|---|---|
| biological source plant (Sunflower) | biological source - | biological source plant | biological source - |
| assay ≥99% (GC) | assay - | assay 90% | assay 65.0-88.0% (GC) |
| functional group oleic acid | functional group - | functional group oleic acid | functional group carboxylic acid |
| solubility H2O: insoluble (practically), benzene: soluble, oil: soluble (fixed and volatile), alcohol: soluble, chloroform: soluble | solubility - | solubility alcohol: soluble, benzene: soluble, chloroform: soluble, diethyl ether: soluble, water: insoluble | solubility - |
| shipped in ambient | shipped in - | shipped in ambient | shipped in - |
| form viscous liquid | form liquid | form liquid, semisolid, waxy solid | form liquid |
Application
- to study the effects of fatty acids on gastric cancer (GC)[1]
- to induce lipid droplet formation in cell culture[2]
- as an additive in the magnetorheological fluid preparation[3].
Biochem/physiol Actions
General description
Other Notes
comparable product
related product
Storage Class
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Articles
How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.
Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
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Can be used in mice?
1 answer-
This product is not tested for use in research animals such as mice. But there certainly is precedence for its use by researchers in a mouse model:
1. https://pubmed.ncbi.nlm.nih.gov/32663612/
See Table 1.
2. https://pubmed.ncbi.nlm.nih.gov/37380774/
See Methods section.Helpful?
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How to store the product after opening the amplue?
1 answer-
The stability of this product in solution has not been determined. However, cell culture supplements containing Oleic acid, available as sterile solutions, are stored at 2-8°C and assigned a shelf life of 1 year. See the table below:
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What solvent is used to resuspend oleic acid in this product?
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This product is a neat or pure liquid that has not been diluted. The recommended solvents are ethanol, methanol, chloroform, and benzene. This information is listed in the 'PROPERTIES' section of the product page.
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What sort of packaging for the vial do you offer ?
1 answer-
The packaging varies according to the quanitity. The 1G package is in a 5 mL clear glass, flat bottom, sealed ampule. The 5G package is in a 10 mL clear glass, flat bottom, sealed ampule. The 25G package is in a 50 mL clear glass, flat bottom, sealed ampule.
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Hello, would OA be soluble in DMSO? Also, after diluting in solvent, how long can it be stored in -20?
1 answer-
Oleic acid is completely miscible with Dimethyl sulfoxide (DMSO) in all proportions. It is generally not recommended to store solutions of unsaturated fatty acids such as oleic acid, due to oxidation. But if the solution is stored under an inert gas (e.g., nitrogen gas or argon gas), that would extend the stability of the solution.
The exact amount of time that the solution is stable is undetermined. Evidence for instability of the solution would be a change in color (colorless to yellow, or yellow to dark yellow, or dark yellow to brown).
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How to sterilize pure oleic acid?
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This product can be sterilized by autoclaving. When diluted in medium or buffer to a working concentration, solutions can be filter-sterilized.
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hello, i would like to know please the concentration of oeic acid in this solution and in what solution we can dissolve it else than chloroform for exemple can we dissolve it in the water and heat (70°C) or in the BSA directly thank you
1 answer-
The solubility information is listed on the product detail page under the "Properties" section as follows:
H2O: insoluble (practically)
alcohol: soluble
benzene: soluble
chloroform: soluble
oil: soluble (fixed and volatile)The concentration for this product will be lot specific as purity changes with each batch. The concentration of this material can be calculated by the equation density x 1000, x purity percent divided by the molecular weight. For example, lot 0000216415 on the sample certificate of analysis will have a concentration of about 3.12 M
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In what solvents can Product O1008, Oleic acid, be dissolved or diluted?
1 answer-
Per the chemicals encyclopedia published by the Royal Society of Chemistry, 12th ed., Entry# 6965, oleic acid is soluble in alcohol, benzene, chloroform, ether, fixed and volatile oils, but is practically insoluble in water.
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