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Merck

PTPRA

protein tyrosine phosphatase, receptor type, A

Sinónimos:
HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Especie:
ID UniProtKB:
ID del gen:
  • Human(5786) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19262) protein tyrosine phosphatase, receptor type, A
  • Rat(25167) protein tyrosine phosphatase, receptor type, A
  • Zebrafish(140818) protein tyrosine phosphatase, receptor type, A
  • chicken(396060) protein tyrosine phosphatase, receptor type, A
  • domestic cat(101096558) protein tyrosine phosphatase, receptor type, A
  • Horse(100066880) protein tyrosine phosphatase, receptor type, A
  • dog(477176) protein tyrosine phosphatase, receptor type, A
  • sheep(101101909) protein tyrosine phosphatase, receptor type, A
  • cow(100138017) protein tyrosine phosphatase, receptor type, A
  • Domestic Rabbit(100342875) protein tyrosine phosphatase, receptor type, A
  • naked mole-rat(101716097) protein tyrosine phosphatase, receptor type, A
  • domestic guinea pig(100720460) protein tyrosine phosphatase, receptor type, A

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-Phospho-PTPRA-Y789 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Milrinone, ≥97% (TLC), powder,
Especie
rat, human

Proteins

Número de producto
Descripción
Especie
PTPRA (174-802), active, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human PTPRA, VPS16,
Especie
human
MISSION® esiRNA, targeting mouse Ptpra,
Especie
mouse