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Merck

CSF1R

colony stimulating factor 1 receptor

Synonyma:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Druh:
ID sady UniProtKB:
ID genu:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

Custom & Knockdown Gene Products

ELISA

Číslo produktu
Popis
Druh
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Druh
human
Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Druh
human

Antibodies

Číslo produktu
Popis
Druhová reaktivita
Aplikace
Anti-Phospho-CSF1R-Y723 antibody produced in rabbit, ,
Druhová reaktivita
human
Aplikace
western blot
Anti-Phospho-CSF1R-Y708 antibody produced in rabbit, ,
Druhová reaktivita
human, mouse, rat
Aplikace
immunohistochemistry
western blot
Anti-CSF-1R antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP211, affinity isolated antibody,
Druhová reaktivita
human, mouse, rat
Aplikace
immunohistochemistry
Anti-CSF-1R/CD115 Antibody clone FER216, clone FER216, from mouse,
Druhová reaktivita
human
Aplikace
western blot
Anti-CSFR antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
human
Aplikace
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Číslo produktu
Popis
Druh
Pazopanib, ,
Druh
human

Proteins

Číslo produktu
Popis
Druh
Fms (Y969C) Protein, active, ,
Druh
human

esiRNA

Číslo produktu
Popis
Druh
MISSION® esiRNA, targeting human CSF1R,
Druh
human
MISSION® esiRNA, targeting mouse Csf1r,
Druh
mouse