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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Synonyma:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Druh:
ID sady UniProtKB:
ID genu:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Číslo produktu
Popis
Druhová reaktivita
Aplikace
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplikace
western blot
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
bovine, canine, guinea pig, horse, human, mouse, rat
Aplikace
immunohistochemistry
western blot
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Druhová reaktivita
human
Aplikace
western blot
Anti-Sodium Channel NaV1.5 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Druhová reaktivita
rat
Aplikace
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Druhová reaktivita
mammals
Aplikace
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Číslo produktu
Popis
Druh
Flecainide acetate salt, ,
Druh
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Druh
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Druh
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Druh
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Druh
human

Small Molecule - Ligand

Číslo produktu
Popis
Druh
Lamotrigine, ≥98%, powder,
Druh
rat, human
Carbamazepine, powder,
Druh
rat, human

esiRNA

Číslo produktu
Popis
Druh
MISSION® esiRNA, targeting human SCN5A,
Druh
human