A0230000

Adenine

Name: Adenine
Brand: SIAL
Price: 3710 CZK

European Pharmacopoeia (EP) Reference Standard

Synonyma:

6-Aminopurine, Vitamin B₄

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Vybrat velikost

50 MG

3 710,00 Kč

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O této položce

Empirický vzorec (Hillův zápis):

C₅H₅N₅

Číslo CAS:

73-24-5

Molekulová hmotnost:

135.13

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329770588

MDL number:

MFCD00041790

Beilstein/REAXYS Number:

5777

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Název produktu

Adenine, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

SMILES string

Nc1ncnc2[nH]cnc12

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

biological source

synthetic

grade

pharmaceutical primary standard

agency

API family

adenine

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

>360 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Související kategorie

Analytical Chemistry

Analytical Reference Materials for Pharma QC

Pharmacopeia & Metrological Institute Standards

Vitamin Standards

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Tato položka	PHR1383	A5665	1152-M
A0230000 Adenine	Supelco PHR1383 Adenine	Sigma-Aldrich A5665 Adenine	Millipore 1152-M Adenine
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) cell culture \| plant: suitable	technique(s) -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) agriculture	application(s) -
format neat	format neat	format -	format -
form solid	form -	form powder	form solid
grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade -	grade -
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. 10-30°C

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Adenine belongs to the group of purine alkaloids widely distributed in plant products and beverages.[1] It can be used as an internal microbial marker for the determination of microbial protein synthesis.[2]

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

related product

Č. produktu

Popis

Stanovení ceny

1012101

Adenine, United States Pharmacopeia (USP) Reference Standard

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral

Skladovací třída

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection

Meyer A, et al.

Fresenius Journal of Analytical Chemistry, 356(3-4), 284-287 (1996)

Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC

Moral dGP, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 826(1-2), 257-260 (2005)

KATP channel interaction with adenine nucleotides.

Michinori Matsuo et al.

Journal of molecular and cellular cardiology, 38(6), 907-916 (2005-05-25)

ATP-sensitive potassium (K(ATP)) channels are regulated by adenine nucleotides to convert changes in cellular metabolic levels into membrane excitability. Hence, elucidation of interaction of SUR and Kir6.x with adenine nucleotides is an important issue to understand the molecular mechanisms underlying

N6-methyl-adenine: an epigenetic signal for DNA-protein interactions.

Didier Wion et al.

Nature reviews. Microbiology, 4(3), 183-192 (2006-02-21)

N(6)-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most bacterial DNA adenine methyltransferases are part of restriction-modification systems. Certain groups of Proteobacteria also harbour solitary DNA adenine methyltransferases that provide signals for DNA-protein interactions. In gamma-proteobacteria

Rilpivirine versus efavirenz with emtricitabine/tenofovir disoproxil fumarate in treatment-naïve HIV-1-infected patients with HIV-1 RNA ≤100,000 copies/mL: week 96 pooled ECHO/THRIVE subanalysis.

Georg Behrens et al.

AIDS patient care and STDs, 28(4), 168-175 (2014-03-26)

The once daily, single-tablet regimen (STR) combining rilpivirine (RPV), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) provides a simplified treatment option for antiretroviral therapy (ART)-naïve patients with baseline HIV-1 RNA (BLVL) of ≤100,000 copies/mL. The aim of this analysis is

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