HomeWebinarsUnderstanding and Optimizing SPME Headspace

Understanding and Optimizing SPME Headspace


What Does it Cover?

This presentation will provide method development guidance for the extraction and quantification of analytes using headspace SPME. The mechanism of headspace SPME will be explained in detail. Methods for enhancing extraction efficiency will be described. Advantages of headspace SPME over other common extraction methods will be highlighted.

What Will You Learn?

  • How to analyse and quantify volatile and semi-volatile compounds using headspace SPME
  • The mechanism behind headspace SPME
  • Methods for enhancing extraction efficiency
  • The advantages of headspace SPME over other extraction methods

Who Should Watch?

Anyone performing, or interested in performing sample preparation prior to chromatographic analysis:

  • Analytical Chemists
  • Method Developers
  • Laboratory Managers, Directors, Supervisors


Robert E. Shirey, M.S.


Principal R&D Scientist

Bob Shirey received his B.S. degree in Chemistry from Shippensburg University and his M.S. degree in Biochemistry from West Virginia University. Bob started working at Supelco in 1984 as an R&D chemist focusing on GC and GC/MS applications. Eventually, Bob started to specialize in sample preparation and played a key role in the development of the VOCARB purge trap line. Since 1993 Bob’s primary responsibilities have been on the development of SPME fibers and hardware along with SPME applications. Bob has written multiple SPME articles for journals and books. Bob continues to focus his efforts on SPME in the development of the BioSPME product line and new SPME coating chemistries. He especially enjoys interacting with customers and learning how they are using the SPME technology.