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Merck

CDC73

cell division cycle 73

Synonyms:
C1orf28, HPTJT, HRPT2, HYX
Species:
UniProtKB ID:
Gene ID:
  • Human(79577) Summary: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
  • Mouse(214498) cell division cycle 73, Paf1/RNA polymerase II complex component
  • Rat(304832) cell division cycle 73
  • Zebrafish(393319) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • dog(478955) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • cow(100139547) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • Horse(100059715) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • domestic cat(101090918) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • sheep(101118545) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • domestic guinea pig(100735298) cell division cycle 73
  • chicken(424356) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
  • naked mole-rat(101726604) cell division cycle 73

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CDC73 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CDC73 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
KD-Validated Anti CDC73 Antibody, clone 23GB3450, Rabbit Monoclonal, clone 23GB3450, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CDC73,
Species
human
MISSION® esiRNA, targeting mouse Cdc73,
Species
mouse