Skip to Content
Merck

CHMP2B

charged multivesicular body protein 2B

Synonyms:
ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B
Species:
UniProtKB ID:
Gene ID:
  • Human(25978) Summary: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
  • Mouse(68942) charged multivesicular body protein 2B
  • Rat(363720) charged multivesicular body protein 2B
  • fruit fly(38599) Charged multivesicular body protein 2b
  • domestic guinea pig(100734811) charged multivesicular body protein 2B
  • naked mole-rat(101717020) charged multivesicular body protein 2B
  • sheep(101121224) charged multivesicular body protein 2B
  • dog(487675) charged multivesicular body protein 2B
  • chicken(418461) charged multivesicular body protein 2B
  • cow(615954) charged multivesicular body protein 2B
  • domestic cat(101099491) charged multivesicular body protein 2B

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHMP2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHMP2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CHMP2B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-CHMP2B antibody produced in mouse, clone 2H6-1E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
KD-Validated Anti CHMP2B Antibody, clone 23GB3070, Rabbit Monoclonal, clone 23GB3070, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHMP2B,
Species
human
MISSION® esiRNA, targeting mouse Chmp2b,
Species
mouse