Polymeric Delivery Platforms
Polymeric platform for delivery of large molecules
The SynBiosys® biodegradable polymer platform makes it possible to create injectable sustained release formulations for virtually any class of biological API, eliminating pharmaceutical development hurdles. SynBiosys® encapsulates proteins and large peptides at high concentrations under gentle process conditions, preserving protein integrity and bioactivity, and can be used for a variety of final drug products.
Key features of the SynBiosys® platform include:
- Suitability for subcutaneous, intramuscular, and site-specific injectable formulations in the form of microparticles and implants with high API doses up to 100 mg/mL
- Duration and rate of API release can be modulated as required, ranging from a few weeks to six months
- Robust and scalable production with high yields and absolute control over particle size (5-100 µm)
- Clinically validated
- Supported by extensive biocompatibility and toxicity data packages, as well as in vivo biocompatibility and degradation data
Related Product Resources
Webinar: Long Acting Injectables – A New Dimension for Proteins and Peptides
Webinar: Critical Quality Factors of Biodegradable Polymers for Injectable Sustained-Release Formulations
Webinar: Polymer Based Drug Delivery Systems for Parenteral Controlled Release - From Small Molecules to Biologics
Flyer: Sustained release of biologicals