F-907

Flunitrazepam -Lösung

Name: Flunitrazepam -Lösung
Brand: CERILLIAN
Price: 54.2 EUR
Availability: InStock

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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Über diesen Artikel

Empirische Formel (Hill-System):

C₁₆H₁₂FN₃O₃

CAS-Nummer:

1622-62-4

Molekulargewicht:

313.28

EG-Nummer:

200-659-6

MDL-Nummer:

MFCD00057906

UNSPSC-Code:

41116107

PubChem Substanz-ID:

329799782

NACRES:

NA.24

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Qualität

certified reference material

Qualitätsniveau

300

Form

liquid

Leistungsmerkmale

Snap-N-Spike^®/Snap-N-Shoot^®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant^®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
kontrollierte Droge in Deutschland

Konzentration

1.0 mg/mL in methanol

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

clinical testing

Format

single component solution

Lagertemp.

−20°C

SMILES String

CN(C1=CC=C([N+]([O-])=O)C=C1C(C2=CC=CC=C2F)=NC3)C3=O

InChI

1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3

InChIKey

PPTYJKAXVCCBDU-UHFFFAOYSA-N

Angaben zum Gen

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

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Dieser Artikel	B-903	L-901	C-909
Supelco F-907 Flunitrazepam -Lösung	Supelco B-903 Bromazepam -Lösung	Supelco L-901 Lorazepam -Lösung	Supelco C-909 Clobazam -Lösung
application(s) clinical testing	application(s) clinical testing	application(s) clinical testing	application(s) clinical testing
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
form liquid	form liquid	form liquid	form liquid
format single component solution	format single component solution	format single component solution	format single component solution
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 300
grade certified reference material	grade certified reference material	grade certified reference material	grade certified reference material

Allgemeine Beschreibung

Certified Spiking Solutions^® are suitable for use in GC/MS or LC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. Flunitrazepam is an intermediate-acting benzodiazepine marketed under the trade name Rohypnol as a hypnotic, sedative, anticonvulsant and skeletal muscle relaxant.

Rechtliche Hinweise

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

A-911

7-Aminoflunitrazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

A-912

7-Aminoflunitrazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

A-921

7-Aminoflunitrazepam-d₇ -Lösung, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

A-925

7-Aminoflunitrazepam-d₇ -Lösung, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

B-905

Benzodiazepine Internal Standard-3 solution, 0.5-1.0 mg/mL in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant^®

D-918

N-Desmethylflunitrazepam -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

D-919

N-Desmethylflunitrazepam -Lösung, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

D-925

N-Desmethylflunitrazepam-d₄, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

F-915

Flunitrazepam-d₇, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

F-093

Flunitrazolam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant^®

F-094

Flunitrazolam-¹³C₂,¹⁵N solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant^®

Piktogramme

GHS02,GHS06,GHS08

Signalwort

Danger

H-Sätze

H225,H301 + H311 + H331,H370

P-Sätze

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup

Zulassungslistungen

Zulassungslistungen werden hauptsächlich für chemische Produkte erstellt. Für nicht-chemische Produkte können hier nur begrenzte Angaben gemacht werden. Kein Eintrag bedeutet, dass keine der Komponenten gelistet ist. Es liegt in der Verantwortung des Benutzers, die sichere und legale Verwendung des Produkts zu gewährleisten.

EU REACH Annex XVII (Restriction List)

CAS No.

67-56-1

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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The Journal of pharmacology and experimental therapeutics, 340(3), 742-749 (2011-12-17)

Adverse effects of benzodiazepines limit their clinical use; these effects might be reduced without altering therapeutic effects by administering other positive GABA(A) modulators (i.e., neuroactive steroids) with benzodiazepines. One concern with this strategy involves reversing these combined effects in case

Decreased GABA(A) benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics.

Virpi Laukkanen et al.

Alcohol (Fayetteville, N.Y.), 47(2), 103-108 (2013-01-22)

Ethanol modulates the GABA(A) receptor to cause sedative, anxiolytic and hypnotic effects that are qualitatively similar to benzodiazepines and barbiturates. The aim of this study was to explore if GABA(A) receptor density is altered in post-mortem brains of anxiety-prone Cloninger

N,N'-dicyclohexylsulfamide and N,N'-diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABA(A) receptor and anxiolytic activity in mice.

Cristina Wasowski et al.

Biochemical pharmacology, 83(2), 253-259 (2011-11-08)

A set of sulfamides designed, synthesized and evaluated against maximal electroshock seizure (MES) and pentilenetetrazol (PTZ) tests with promising results, were tested for their affinity for the benzodiazepine binding site of the GABA(A) receptor. The most active compounds, N,N'-dicyclohexylsulfamide (7)

The mass transfer dynamics of hollow fiber liquid-phase microextraction and its application for rapid analysis of biological samples.

Shufen Cui et al.

Journal of chromatography. A, 1266, 10-16 (2012-11-03)

Hollow fiber liquid-phase microextraction (HF-LPME) has been demonstrated to potentially become a mainstream sample preparation technique for complex samples. Nevertheless, the need for a relatively long extraction time is considered to be the major disadvantage of this method. Lengthy extractions

Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis.

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Biochemical pharmacology, 83(12), 1690-1699 (2012-03-27)

Nitrobenzodiazepine (NBDZ) is an addictive drug of the abused substances that causes severe neurological effects and even death. Bacterial type I nitroreductase NfsB (EC 1.5.1.34) has been reported to catalyze NBDZ into inactive metabolite 7-amino-benzodiazepine (7ABDZ) with promising activity, so

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