104981

6-Bromopurine

98%

• Empirical Formula (Hill Notation): C₅H₃BrN₄
• CAS Number: 767-69-1
• Molecular Weight: 199.01
• EC Number: 212-187-8
• MDL number: MFCD00022648
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846685
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: solid
• mp: >300 °C (lit.)
• functional group: bromo
• SMILES string: Brc1ncnc2nc[nH]c12
• InChI: 1S/C5H3BrN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
• InChI key: CTGFGRDVWBZYNB-UHFFFAOYSA-N

Description

General description

6-Bromopurine enhances the carcinostatic activity of azaserine in a test system employing ascites cell forms of sarcoma 180 and Ehrlich carcinoma in vivo[1]. 6-bromopurine nucleosides are excellent substrates for substitution reactions with N-, O-, and S-containing nucleophiles in polar solvents[2].

Application

6-Bromopurine was used in the synthesis of 6-halopurine alkynes and corresponding triazole derivatives[3]. 6-Bromopurine was used in the synthesis and chemical characterization of 2,3,4,5-tetrahydro-1,5-benzoxazepines-3-ol[4].

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves