Merck
  • L040030
All Photos(1)

L040030

Sigma-Aldrich

Cap A

configured for ABI

All Photos(1)
NACRES:
NA.21

type

for DNA synthesis

Quality Level

200

product line

Proligo Reagents

shelf life

365 days

concentration

97.0-119.0 g/L (Acetic Anhydride content, titration)

color

clear colorless, to brownish

compatibility

configured for ABI

storage temp.

2-8°C

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1 of 4

This Item
L040080L040050L050030
Sigma-Aldrich

Sigma-Aldrich

L040030

Cap A

Sigma-Aldrich

Sigma-Aldrich

L040080

Cap A

Sigma-Aldrich

Sigma-Aldrich

L040050

Cap A

Sigma-Aldrich

Sigma-Aldrich

L050030

Cap B

type

for DNA synthesis

type

for DNA synthesis

type

for DNA synthesis

type

for DNA synthesis

product line

Proligo Reagents

product line

Proligo Reagents

product line

Proligo Reagents

product line

Proligo Reagents

shelf life

365 days

shelf life

-

shelf life

-

shelf life

-

concentration

97.0-119.0 g/L (Acetic Anhydride content, titration)

concentration

88.7-108.4 g/L (Acetic Anhydride content, titration)

concentration

-

concentration

-

color

clear colorless, to brownish

color

clear

color

clear

color

clear

compatibility

configured for ABI

compatibility

configured for PerkinElmer, configured for Polygen

compatibility

configured for (ÄKTA® and OligoPilot®)

compatibility

configured for ABI

General description

Cap A solution contains acetic anhydrideanhydride, lutidine and tetrahydrofuran (THF). It is used after the phosphoramidite reaction/coupling step. The solution is configured for ABI.

Biochem/physiol Actions

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

Preparation Note

Tetrahydrofurane / Lutidine / Acetic Anhydride 8/1/1 (v/v/v)

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

6.1 °F

Flash Point(C)

-14.4 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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