L050030

Cap B

configured for ABI

• NACRES: NA.21

Properties

• type: for DNA synthesis
• Quality Level: 200
• product line: Proligo Reagents
• storage condition: dry at room temperature
• impurities: ≤200 ppm water content (Karl Fischer)
• color: clear
• suitability: conforms to structure (GC, Formulation)
• compatibility: configured for ABI

Description

General description

Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Preparation Note

Tetrahydrofurane / N-Methylimidazole 84/16 (v/v)

Other Notes

Cap B solution, containing tetrahydrofuran (THF) and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Lutidine is applied as a mild base while NMI provides a powerful acylation catalyst.

Safety Information

• Pictograms: GHS02,GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H302 - H314 - H335 - H336 - H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 6.1 °F
• Flash Point(C): -14.4 °C