Merck
  • L050150
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L050150

Sigma-Aldrich

Cap B2

configured for (ÄKTA® and OligoPilot®)

Synonym(s):
Cap B
NACRES:
NA.21

type

for DNA synthesis

Quality Level

product line

Proligo Reagents

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)

color

clear

suitability

conforms to structure (GC, Formulation)

compatibility

configured for (ÄKTA® and OligoPilot®)

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1 of 4

This Item
L040050L050050L050030
Sigma-Aldrich

Sigma-Aldrich

L050150

Cap B2

Sigma-Aldrich

Sigma-Aldrich

L040050

Cap A

Sigma-Aldrich

Sigma-Aldrich

L050050

Cap B1

Sigma-Aldrich

Sigma-Aldrich

L050030

Cap B

type

for DNA synthesis

type

for DNA synthesis

type

for DNA synthesis

type

for DNA synthesis

product line

Proligo Reagents

product line

Proligo Reagents

product line

Proligo Reagents

product line

Proligo Reagents

storage condition

dry at room temperature

storage condition

dry at room temperature

storage condition

dry at room temperature

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)

impurities

≤100 ppm water content (Karl Fischer)

impurities

-

impurities

≤200 ppm water content (Karl Fischer)

color

clear

color

clear

color

-

color

clear

suitability

conforms to structure (GC, Formulation)

suitability

conforms to structure (GC, Formulation)

suitability

conforms to structure (GC, Formulation)

suitability

conforms to structure (GC, Formulation)

General description

Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.Tetrahydrofurane has been replaced by acetonitrile in ÄKTA Cap B1 and B2.Cap B is configured for ÄKTA formulation.

Preparation Note

Acetonitrile / Pyridine 4/6 (v/v)

Other Notes

Cap B2 solution, containing acetonitrile (ACN) and pyridine, is mixed in situ with Cap A and Cap B1 solution during the capping (acetylation) reaction.
Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Legal Information

OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

62.6 °F

Flash Point(C)

17 °C


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