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850511P

Avanti

n-octyl-β-D-glucoside

Avanti Polar Lipids

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Synonym(s):
octyl glucoside; OG; OGP
Empirical Formula (Hill Notation):
C14H28O6
CAS Number:
Molecular Weight:
292.37
UNSPSC Code:
12161902
NACRES:
NA.25

description

n-octyl-β-D-glucopyranoside

Assay

>99% (contains <0.2% alpha isomer, TLC)

form

powder

mol wt

292.37 g/mol

packaging

pkg of 1 × 1 g (850511P-1g)
pkg of 1 × 5 g (850511P-5g)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](OCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

InChI key

HEGSGKPQLMEBJL-RKQHYHRCSA-N

General description

n-octyl-β-D-glucoside (βOG) is a non-ionic detergent. It has a eight carbon hydrophobic tail.
Octyl glucoside is a dialyzable nonionic detergent for functional solubilization and purification of membrane proteins.

Application

n-octyl-β-D-glucoside is suitable for use to study its self-diffusion coefficients in α-cyclodextrin and β-cyclodextrin solutions at 25°C. 

Biochem/physiol Actions

n-octyl-β-D-glucoside (βOG) helps to extract, solubilize and denature membrane proteins. Octyl glucoside has versatile uses including: reconstituting an ion channel, solubilizing an enzyme and incorporating a protein into liposomes. Also, nonionizing detergent complexes are used in protein crystallization studies. It is mainly used in the expression and purification of recombinant protein.

Packaging

20 mL Clear Glass Screw Cap Vial (850511P-1g)
30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850511P-5g)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Interactions between n-octyl and n-nonyl beta-D-glucosides and alpha-and beta-cyclodextrins as seen by self-diffusion NMR
Valente AJM, et al.
Journal of Colloid and Interface Science, 281(1), 218-224 (2005)
A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding
Wu M, et al.
Testing, 13(2), e0192512-e0192512 (2018)
APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein
Alce TM and Popik W
The Journal of Biological Chemistry, 279(33), 34083-34086 (2004)

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