429415

L-α-Lecithin

≥97% (choline basis), solid, lipotropic agent, Calbiochem

• Synonym(s): L-α-Lecithin, Soybean
• CAS Number: 8002-43-5
• MDL number: MFCD00131449
• UNSPSC Code: 12352211
• NACRES: NA.77

Properties

• Product Name: L-α-Lecithin, Soybean, L-α-Lecithin, Soybean, CAS 8002-43-5, is a concentrate of soybean lecithin consisting of more than 94% phosphatidylcholine and less than 2% triglycerides.
• Quality Level: 100
• description: Merck USA index - 14, 5428
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: light yellow
• solubility: RPMI culture medium: 10 mg/mL, turbid; chloroform: 200 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C\C\C=C\CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14+,21-20+/t40-/m1/s1
• InChI key: JLPULHDHAOZNQI-JLOPVYAASA-N

Description

General description

Concentrate of soybean lecithin consisting of more than 94% phosphatidylcholine and less than 2% triglycerides. Composed mainly of linoleic acid (62 - 65%) and palmitic acid (15 - 17%) esters.

Lecithins are typically phospholipids, consisting of phosphoric acid with choline, glycerol, and one (lyso-forms) or two fatty acids.[1] It is a yellow to brown fatty substance, that can be obtained from both plant and animal sources, with soy lecithin and sunflower lecithin being common varieties.[2] They are present in animal products due to dietary sources and de novo synthesis.[1] Commercial lecithin, often derived from soybeans, is widely employed in the food industry as an emulsifier in processed goods such as ice creams and salad dressings.[2] Lecithin supplements are commonly used to manage high cholesterol levels, support lactation, and serve as antiulcer agents. Lecithin, also known as phosphatidylcholine, serves as a precursor for choline and is involved in the synthesis of the neurotransmitter acetylcholine, with its levels correlating with those of choline and acetylcholine. Moreover, it plays a role in complex intracellular processes, including the regulation of cellular membrane permeability.[3]

Application

L-α-Lecithin, Soybean has been used in film preparation[4] and as a surfactant for the preparation and characterization of the nanoemulsion.[4] It has also been used as a component in solubilization buffer to incubate heavy SR (HSR) for affinity purification of RyR1 (ryanodine receptor).[5]

Biochem/physiol Actions

Cell permeable: no

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable