16301

D-(+)-Glucose monohydrate

meets analytical specification of Ph. Eur., BP, Ph Franç., 7.0-9.5% water(Karl Fischer)

• Synonym(s): Dextrose monohydrate
• Empirical Formula (Hill Notation): C₆H₁₂O₆ · H₂O
• CAS Number: 14431-43-7
• Molecular Weight: 198.17
• Beilstein: 5250278
• EC Number: 218-914-5
• MDL number: MFCD00149450
• PubChem Substance ID: 57647555
• NACRES: NA.21

Properties

• Assay: 97.5-102.0% anhydrous basis (HPLC)
• Quality Level: 200
• form: powder
• optical activity: [α]20/D +52.5 to +53.3°, c = 10% in H₂O (calc. on anhydrous subst.)
• quality: meets analytical specification of Ph. Eur., BP, Ph Franç.
• impurities: residual solvents, complies; 7.0-9.5% water (Karl Fischer)
• ign. residue: ≤0.1% (as SO₄)
• solubility: H₂O: 10g/5 mL, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfite (SO₃^2-): ≤15 ppm
• cation traces: Al: ≤0.5 mg/kg; As: ≤1 mg/kg; Ba:, in accordance; Ca: ≤200 mg/kg; Pb: ≤0.5 mg/kg
• SMILES string: O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O
• InChI: 1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1
• InChI key: SPFMQWBKVUQXJV-BTVCFUMJSA-N

Description

Application

D-(+)-Glucose monohydrate has been used as a test compound for studying its dehydration kinetics by using THz time-domain spectroscopy (THz-TDS).

Biochem/physiol Actions

D-(+)-Glucose is a common natural sugar involved in key cellular processes of energy production, glycosylation and formation of glycans that provide structure to cells. Glucose is involved in post-translational modifications of proteins by glycation or non-enzymatic glycosylation of proteins at the lysine residues. Glycation is detrimental and results in complications associated with diabetes mellitus, alzheimer′s disease, aging and cataract.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves