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31707

Supelco

Dimetridazole

VETRANAL®, analytical standard

Synonym(s):
1,2-Dimethyl-5-nitroimidazole
Empirical Formula (Hill Notation):
C5H7N3O2
CAS Number:
Molecular Weight:
141.13
Beilstein:
130665
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ncc(n1C)[N+]([O-])=O

InChI

1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3

InChI key

IBXPYPUJPLLOIN-UHFFFAOYSA-N

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This Item
M37613419634004
Dimetridazole VETRANAL®, analytical standard

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31707

Dimetridazole

Metronidazole analytical standard

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M3761

Metronidazole

Dimetridazol-d3 analytical standard

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Dimetridazol-d3

Ipronidazole-OH VETRANAL®, analytical standard

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34004

Ipronidazole-OH

format

neat

format

neat

format

neat

format

neat

product line

VETRANAL®

product line

-

product line

-

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

clinical testing

application(s)

forensics and toxicology
pharmaceutical (small molecule)

General description

Dimetridazole (DMZ) is a 5-nitroimidazole type veterinary drug mostly used for treating infections caused by bacteria and protozoa. These infections can be frequently seen in the poultry industry.

Application

Dimetridazole has been used as reference standard for determination of DMZ concentration from poultry muscles, porcine kidney and liver, and chicken liver tissues using gas chromatography–electron capture negative ionization mass spectrometry (GC–ECNI-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Determination of dimetridazole and metronidazole in poultry and porcine tissues by gas chromatography?electron capture negative ionization mass spectrometry.
Ho, Clare, et al.
Analytica Chimica Acta, 530.1, 23-31 (2005)
M Sánchez-Polo et al.
Water research, 43(16), 4028-4036 (2009-06-23)
The main objectives of this study were: (1) to investigate the decomposition and mineralization of nitroimidazoles (Metronidazole [MNZ], Dimetridazole [DMZ], and Tinidazole [TNZ]) in waste and drinking water using gamma irradiation; (2) to study the decomposition kinetics of these nitroimidazoles;
M G Müller et al.
Veterinary parasitology, 152(1-2), 67-78 (2008-01-02)
Four falcons from a private collection of 137 falcons in Abu Dhabi (UAE) died suddenly in summer 2005. In order to screen for a possible disease among the remaining falcons in the aviary, all other birds were caught, examined and
J H Wang
Journal of chromatography. A, 918(2), 435-438 (2001-06-16)
A method was developed for the determination of the nitroimidazole compounds dimetridazole (DMZ), ronidazole (RNZ) and metronidazole (MNZ) by gas chromatography with nitrogen phosphorus detection. Nitroimidazole compounds were extracted with acetonitrile, followed by acidification using acetic acid and cleanup using
Jianzhong Shen et al.
Journal of AOAC International, 86(3), 505-509 (2003-07-11)
A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the

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