34124

Deoxynivalenol solution

100 μg/mL in acetonitrile, analytical standard

• Synonym(s): 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one, DON, Vomitoxin
• Empirical Formula (Hill Notation): C₁₅H₂₀O₆
• CAS Number: 51481-10-8
• Molecular Weight: 296.32
• EC Number: 200-835-2
• MDL number: MFCD09039270
• UNSPSC Code: 85151701
• PubChem Substance ID: 329754831
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• shelf life: limited shelf life, expiry date on the label
• concentration: 100 μg/mL in acetonitrile
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: single component solution
• storage temp.: −20°C
• SMILES string: CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O
• InChI: 1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1
• InChI key: LINOMUASTDIRTM-QGRHZQQGSA-N

Description

General description

Deoxynivalenol belongs to the group of tetracyclic sesquiterpenoid mycotoxins called trichothecenes[1], produced by Fusarium fungi, naturally occurring in small grains and infected corn.[2]

Check out our entire range of trichothecene type mycotoxin reference materials

Deoxynivalenol is frequently found in cereals and agricultural products including, corn, barley, oats, rye, maize, wheat, malt, bread, beer, etc.[3] It is a mycotoxin and primarily affects the livestock industry by reducing the food intake in farm animals. The effect of DON contamination in cereals and other food samples serves as one of the factors of Kashin-Beck disease, a chronic and endemic osteoarticular disorder.[4]

Application

Deoxynivalenol solution has been used as an analytical reference standard for the quantification of the analyte in cornmeal and wheat meal matrices using high-performance liquid chromatography with UV detection (HPLC-UV). It is used as an analytical standard in investigating its toxicity mechanism on human chondrocytes by microarray and bioinformatics analysis.[4]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves