Merck
  • A214630
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A214630

Sigma-Aldrich

DMT-2′O-TC-rA(ib) Phosphoramidite

configured for ABI

Synonym(s):
DMT-2′O-TC-rA(ib) Amidite
Empirical Formula (Hill Notation):
C49H61N8O10PS2
CAS Number:
Molecular Weight:
1017.16

Assay

≥98% (31P-NMR)
≥98.0% (reversed phase HPLC)

Quality Level

technique(s)

oligo synthesis: suitable

impurities

≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR)
≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC)

compatibility

configured for ABI

nucleoside profile

base: adenosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT

storage temp.

-10 to -25°C

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This Item
G211030G211630A211030
assay

≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

technique(s)

oligo synthesis: suitable

technique(s)

oligo synthesis: suitable

technique(s)

oligo synthesis: suitable

technique(s)

oligo synthesis: suitable

impurities

≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR)

impurities

≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (reversed phase HPLC), ≤3% residual Solvent content

impurities

≤0.3 wt. % water content (Karl Fischer), ≤0.5% 3′-TC isomer (reversed phase HPLC), ≤0.5% P(III) Impurities 145-155ppm (31P-NMR)

impurities

≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (reversed phase HPLC), ≤3% residual Solvent content

compatibility

configured for ABI

compatibility

configured for ABI

compatibility

configured for ABI

compatibility

configured for ABI

nucleoside profile

base: adenosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT

nucleoside profile

base: guanosine
base protecting group: isobutyryl
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard

nucleoside profile

base: guanosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT
deprotection: fast

nucleoside profile

base: adenosine
base protecting group: benzoyl
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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