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G5767

Sigma-Aldrich

D-(+)-Glucose

ACS reagent

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Synonym(s):
Dextrose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

wheat

Quality Level

grade

ACS reagent

form

powder

optical activity

[α]25/D +52.5 to +53.0°(lit.)

impurities

Starch, passes test
≤0.002 meq/g Titratable acid
≤0.005% Insoluble matter

ign. residue

≤0.02%

loss

≤0.2% loss on drying, 105°C

color

colorless

mp

150-152 °C (lit.)

anion traces

chloride (Cl-): ≤0.01%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Application

D-(+)-Glucose has been used:
  • as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
  • as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
  • to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
  • for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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