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EHU135341

Sigma-Aldrich

MISSION® esiRNA

targeting human ACSS2

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NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AATGAGTCCGGGGAAGAGTTGGAAGGTGAAGCTGAAGGTTATCTGGTGTTCAAGCAGCCCTGGCCAGGGATCATGCGCACAGTCTATGGGAACCACGAACGCTTTGAGACAACCTACTTTAAGAAGTTTCCTGGATACTATGTTACAGGAGATGGCTGCCAGCGGGACCAGGATGGCTATTACTGGATCACTGGCAGGATTGATGACATGCTCAATGTATCTGGACACCTGCTGAGTACAGCAGAGGTGGAGTCAGCACTTGTGGAACATGAGGCTGTTGCAGAGGCAGCTGTGGTGGGCCACCCTCATCCTGTGAAGGGTGAATGCCTCTACTGCTTTGTCACCTTGTGTGATGGCCACACCTTCAGCCCCAAGCTCACCGAGGAGCTCAAGAAGCAGATTAGAGAAAAGATTGGCCCCAT

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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MISSION® esiRNA targeting human ACSS2

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MISSION® esiRNA targeting human HES6

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MISSION® esiRNA targeting human ZC4H2

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EHU064561

MISSION® esiRNA

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

esiRNA cDNA target sequence

AATGAGTCCGGGGAAGAGTTGGAAGGTGAAGCTGAAGGTTATCTGGTGTTCAAGCAGCCCTGGCCAGGGATCATGCGCACAGTCTATGGGAACCACGAACGCTTTGAGACAACCTACTTTAAGAAGTTTCCTGGATACTATGTTACAGGAGATGGCTGCCAGCGGGACCAGGATGGCTATTACTGGATCACTGGCAGGATTGATGACATGCTCAATGTATCTGGACACCTGCTGAGTACAGCAGAGGTGGAGTCAGCACTTGTGGAACATGAGGCTGTTGCAGAGGCAGCTGTGGTGGGCCACCCTCATCCTGTGAAGGGTGAATGCCTCTACTGCTTTGTCACCTTGTGTGATGGCCACACCTTCAGCCCCAAGCTCACCGAGGAGCTCAAGAAGCAGATTAGAGAAAAGATTGGCCCCAT

esiRNA cDNA target sequence

CCAGCATGCCAAGAGACATCTACCAAGATTATACTCAAGACTCTTTCAGTATACAAGATGGGAATTCTCAGTATTGTGATTCATCAGGATTCATTCTCACAAAAGACCAGCCTGTAACAGCCAACATGTATTTTGACAGTGGGAACCCTGCCCCAAGCACCACATCACAGCAGGCAAACTCTCAGTCAACTCCTGAGCCTTCACCATCACAGACATTTCCCGAGTCTGTGGTAGCCGAGAAGCAGTATTTTATTGAAAAATTAACGGCGACAATCTGGAAGAACCTTTCTAATCCAGAAATGACTTCTGGATCTGATAAAATTAATTATACATATATGTTAACTCGTTGTATTCAGGCGTGTAAGACAAATCCTGAGTATATATATGCTCCTTTAAAGGAAATTCCTCCTGCCGACATC

esiRNA cDNA target sequence

CCCTGAGGCTGAACTGAGTCAGGCTCCTGCTGAGGGGCCCGACTTGGTGCCCGCAGCCCTGGGCAGCCTGACCACAGCCCAAATTGCCCGGAGTGTCTGGAGGCCTTGGTGACCAATGCCAGCCAGAGTCCTGCGGGGGTGGGCCCGGCCCTCCCTGGATCTCCTCCCTCCTCCCAGGGGTTCAGATGTGGTGGGGTAGGGCCCTGGAAGTCTCCCAGGTCTTCCCTCCCTCCTCTGATGGATGGCTTGCAGGGCAGCCCCTGGTAACCAGCCCAGTCAGGCCCCAGCCCCGTTTCTTAAGAAACTTTTAGGGACCCTGCAGCTCTGGAGTGGGTGGAGGGAGGGAGCTACGGGCAGGAGGAAGAATTTTGTAGAGCTGCCAGCGCTCTCCCAGGTTCACCCACCCAGGCTTCACCAGCCCTGTGCGGGCTCTGGGGGCAGAGGTGGCAGAAATGGTGCTGGGCACTAGT

esiRNA cDNA target sequence

CCTTAAGGCCCAGAGGTAGCTTGGACAAGCCCTCCTTTTCATAATCATTTGGGAGGCATGGCTGTAATTCTTTAGCTTTCTCCACTTCTGTCTCCCACATATACTAAAATTCTTAGGTACTAGGCTGTGTGTCTTGGGATCTTAAGATCAATGAACCTTTCCCCAATATCTAGTCTTTGCAAATTCTAGTAGAAGATTTCCACAGTGAAATCAGTGAGCCAGACCAACTCTACATCTCCTGCCTAACCTACTGCCTAAGTCATTAGGGCTGAGGGCTCGGCTGTAGGGGCTTCCTTAGGCTGAGAGTGCCCCCAGGCTGACATCTGTGTTGGCTTTTGTTCAGAACCATTACTCTGGCACATGCTCAATGGTATATTGCAGGGAGGAGAGGAGTAGATTTAGATTTGAGTAAATGCCAATCACTTTACACATGAAGGTGGGTGGGACTTTCCTTCCATTCATCCCTTG

Ensembl | human accession no.

ENSG00000131069

Ensembl | human accession no.

ENSG00000186416

Ensembl | human accession no.

ENSG00000144485

Ensembl | human accession no.

ENSG00000126970

NCBI accession no.

NM_001076552

NCBI accession no.

NM_017544

NCBI accession no.

NM_018645

NCBI accession no.

NM_018684

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Lin Sun et al.
Cancer science, 108(7), 1338-1346 (2017-04-08)
Metastasis is a serious risk that may occur during the treatment of hepatocellular carcinoma (HCC), preventing many patients from being surgical candidates and contributing to poor prognosis. Hypoxia has been proved an important factor of metastasis through the epithelial-mesenchymal transition
Joab Otieno Odera et al.
The Biochemical journal, 477(16), 3075-3089 (2020-08-11)
Alcohol drinking is a leading risk factor for the development of esophageal squamous cell carcinoma (ESCC). However, the molecular mechanisms of alcohol-associated ESCC remain poorly understood. One of the most commonly mutated genes in ESCC is nuclear factor erythroid 2

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