F2878

Ficoll^® PM 70

Type 70

• Synonym(s): Poly(sucrose-co-epichlorhydrin)
• CAS Number: 72146-89-5
• MDL number: MFCD00131071
• UNSPSC Code: 12352201
• NACRES: NA.25

Properties

• type: Type 70
• Quality Level: 200
• form: powder
• mol wt: ~70,000
• color: white
• solubility: H₂O: soluble 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

Description

General description

Ficoll^® PM70, a high molecular weight branched polysaccharide polymer, is believed that they do not contain any ionized groups. This sucrose-polymer is formed by the copolymerization of sucrose with epichlorhydrin.

Application

Ficoll^® PM 70 has been used:

• as a macromolecule in a comparative study to evaluate its effect in vitrification solutions
• as a supplement in the vitrification solution for the vitrification procedure of oocytes
• as a component of low serum medium for human lung fibroblast cell culture to promote a crowded environment

Biochem/physiol Actions

Ficoll is commonly used as a macromolecular constituent of vitrification solutions. Due to their dense branching, Ficolls also serve as ideal, nearly spherical molecular crowding agents.

Ficoll^TM PM 70 is used as a macromolecular crowding agent in studies of cell volume signaling and protein refolding.[1]It may be used in tissue engineering and macromolecular conformation research for the development, evaluation, and use of macromolecular crowding (MMC) systems and configurations. Ficoll PM-70 can also be used in vitrification research.

Other Notes

A nonionic synthetic polymer of sucrose.

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

Ficoll is a registered trademark of Cytiva

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves