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G111000

DMT-dG(ib) Phosphoramidite

Synonym(s):

DMT-dG(ib) amidite, Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

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6 x 10 g

Available to ship TODAYfromHamburg

€1,030.00
100 g
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€1,580.00
6 x 20 g
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€1,880.00
210.1 g
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€3,240.00
500 g
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€6,850.00
20 x 40 g
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€13,700.00
1 kg
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About This Item

Empirical Formula (Hill Notation):
C44H54N7O8P
CAS Number:
Molecular Weight:
839.92
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Assay:
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
Biological source:
non-animal source (no BSE/TSE risk)
Form:
powder or granules
Solubility:
0.1 g/L at 68 °F
Storage temp.:
2-8°C

€1,030.00


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biological source

non-animal source (no BSE/TSE risk)

Quality Segment

type

for DNA synthesis

product line

Proligo Reagents

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

form

powder or granules

technique(s)

oligo synthesis: suitable

impurities

≤0.3 wt. % water content (Karl Fischer)

color

white to off-white

solubility

0.1 g/L at 68 °F

λ

conforms (UV/VIS Identity)

nucleoside profile

base: deoxyguanosine
base protecting group: isobutyryl
2' protecting group: none
5' protecting group: DMT
deprotection: standard

storage temp.

2-8°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(NC(=O)C(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6

InChI

1S/C44H54N7O8P/c1-28(2)41(52)48-43-47-40-39(42(53)49-43)46-27-50(40)38-25-36(59-60(57-24-12-23-45)51(29(3)4)30(5)6)37(58-38)26-56-44(31-13-10-9-11-14-31,32-15-19-34(54-7)20-16-32)33-17-21-35(55-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H2,47,48,49,52,53)/t36-,37+,38+,60?/m0/s1

InChI key

FDRMKYVTIFSDPR-MMROLVBFSA-N

General description

DMT-dG(ib) Phosphoramidite belongs to the group of DNA Phosphoramidites.Its key features include:

  • Exocyclic amine functions are protected by a benzoyl group (dA(bz) anddC(bz)) or isobutyryl group (dG(ib))
  • Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
  • The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides

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This Item
G111040G111050G111080
biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder or granules

form

powder or granules

form

powder or granules

form

powder or granules

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

solubility

0.1 g/L at 68 °F

solubility

-

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C


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