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G8769

Sigma-Aldrich

D-(+)-Glucose solution

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

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Synonym(s):
D-Glucopyranose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1281608
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

sterility

sterile-filtered

Quality Level

product line

BioXtra

form

solution

concentration

45% in H2O

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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This Item
G8644G5146G6152
D-(+)-Glucose solution 45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

G8769

D-(+)-Glucose solution

D-(+)-Glucose solution 100 g/L in H2O, sterile-filtered, BioXtra, suitable for cell culture

G8644

D-(+)-Glucose solution

D-(+)-Glucose Hybri-Max™, powder, BioReagent, suitable for hybridoma

G5146

D-(+)-Glucose

D-(+)-Glucose suitable for mouse embryo cell culture, ≥99.5% (GC)

G6152

D-(+)-Glucose

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

200

form

solution

form

solution

form

powder

form

powder

product line

BioXtra

product line

BioXtra

product line

BioReagent

product line

-

impurities

endotoxin, tested

impurities

endotoxin, tested

impurities

endotoxin, tested

impurities

-

sterility

sterile-filtered

sterility

sterile-filtered

sterility

-

sterility

-

General description

Glucose is the energy currency essential for physiological processes in the living cells. It serves as a precursor for glycoproteins, glycolipids and glycosaminoglycans.

Application

D-(+)-Glucose solution has been used as a medium supplement:
  • in Dulbecco′s Modified Eagle Medium (DMEM) for culturing Flp-In  293 cells
  • in dissection medium for coronal slices from rat brain
  • in neurobasal medium for culturing hippocampi cells

Provides the primary energy source for cell metabolism.

Biochem/physiol Actions

Glucose is a crucial component for the growth and maintenance of mammalian cells in in vitro conditions and is essential for productivity and quality. Its high metabolic turnover favors osteoclast differentiation. The levels of glucose modulate the migration and growth of tumor cells. HeLa cells display high mobility at low glucose levels.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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25G
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Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress
Ishida T, et al.
Micromachines, 7(9), 155-155 (2016)
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
Vergara M, et al.
Testing, 13(8), e0202098-e0202098 (2018)
Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator
Mobasheri A
Frontiers in Endocrinology, 3, 153-153 (2012)
Protein kinase C activation causes neurite retraction via cyclin D 1 and p60-katanin increase in rat hippocampal neurons
Korulu S, et al.
The European Journal of Neuroscience, 37(10), 1610-1619 (2013)
Chad A Dumstorf et al.
Molecular cancer therapeutics, 9(12), 3158-3163 (2010-10-26)
Enzastaurin (LY317615.HCl) is currently in a phase III registration trial for diffuse large B-Cell lymphoma and numerous phase II clinical trials. Enzastaurin suppresses angiogenesis and induces apoptosis in multiple human tumor cell lines by inhibiting protein kinase C (PKC) and

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