Manufacturing the final dosage form of a small molecule drug requires robust quality and design in development of the formulation and production of the final product. Explore solutions and best practices to advance and accelerate small molecule pharmaceuticals, from development
Cell-to-cell variability can be due to a number of reasons; e.g., non-uniformity of the cellular environment, enetic differences resulting from mutations or stochastic events in gene expression. Here, We presenting the new MAMS for single-cell analysis.
For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods for accurate assessment of drug efficacy. Industrial trends toward highly specific LC/MS applications over traditional immunoassay have resulted in the need
As the world’s leading supplier of oligonucleotides, we deliver the largest portfolio of capabilities and expertise to our commercial partners. Now we have upgraded our facilities to ISO 13485:2003 to better support your diagnostic manufacturing needs.
Understanding the role of chirality in pharmacology became extremely important following the tragedy of thalidomide use in the 1960s. At that time the effect of chirality was poorly understood, and whilst it was discovered that the sedative effect resided in
Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.
Due to stricter safety regulations, shipment of diethyl azodicarboxylate (DEAD) as a dry reagent is prohibited in the United States. We have achieved full compliance with UN and U.S. DOT safety regulations, and is pleased to offer this extremely versatile
TPGS-750-M, a second generation surfactant, is useful for room temperature, palladium and ruthenium-catalyzed reactions in water. Reactions include the Heck reaction, Suzuki-Miyaura reaction, Sonogashira reaction, Buchwald-Hartwig amination reaction, Negishi reaction, and olefin metathesis.
Alcohol oxidation is one of the most frequently performed oxidation reactions in organic chemistry. The aldehyde and ketone products of alcohol oxidation are useful intermediates en route to complex molecules.
Although antibody-drug conjugates show promise in the development of effective cancer therapies, there are still a variety of challenges involved in enabling the safe manufacture of these hazardous drugs.
Beyond meeting essential nutritional needs, functional foods promote better health by reducing the risk of chronic disease such as coronary heart disease and cancer, improving cognitive health, and managing weight.
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
Rhamnolipids (Cat # L510025) are some of the best known and most often tested biosurfactants. AGAE Technologies has developed a process to produce R-95 HPLC/MS Grade rhamnolipids