The Oligonucleotide reagents manufacturing site in Hamburg, Germany is designed as a multi-purpose facility with built-in flexibility and the capability to manufacture a complex mix of products to suit a variety of customer needs.
DNA and RNA phosphoramidites are manufactured in glass-lined reactors and purified by preparative column chromatography on silica gel with medium-to-high pressure chromatography equipment.
The Hamburg facility has the flexibility to prepare and purify alternative mixes of high volume standard products as well as small-scale specialties.
Process Technology and R&D
Production and Purification
Over 40 years’ experience in the manufacture of Oligonucleotide reagents:
Annual amidite production capacity is more than 12 tons and increasing annually, to meet the growing industry demands. All critical raw materials are dual sourced to ensure continuity of supply
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